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Neurofibromatosis Type I: Lisch Nodules The tan mounds on the iris are melanotic hamartomas present in over 90% of patients with Neurofibromatosis Type 1 after age 6. They are hard to recognize without a biomicroscope and do not affect vision.
Other ophthalmic complicationsOptic nerve and chiasm pilocytic astrocytomas are found in 15% of Neurofibromatosis Type 1 patients. These are very indolent neoplasms that may not grow. In 50% of cases, they impair vision.Treatment for growing optic pathway astrocytomas is radiation or chemotherapy. Both methods may halt growth, but reversal of vision loss is rare. Neurofibromatosis Type 1 patients also get plexiform neurofibromas on the eyelids and glaucoma. When eyelid masses are present, 50% of patients have glaucoma.
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 An interactive teaching and assessment program on vision care
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